Semaglutide is a member of one of the newest classes of medications called GLP-1 agonists. These agonists were initially used to treat Type-2 diabetes, but many patients also lost a significant amount of weight and experienced a lot of other health benefits including a reduction of cardiovascular events such as coronary artery disease and stroke, prevention and regression of Type-2 diabetes. Semaglutide is maximally effective for weight loss at doses that are significantly higher than what is currently recommended for the treatment of Type-2 diabetes.
Semaglutide is marketed under the names of Ozempic™ and Rybelsus™ for the treatment of Type-2 Diabetes. Semaglutide is sold under the name of Wegovy™ for the treatment of obesity and in patients that are overweight who also have other cardiometabolic risk factors such as hypertension, pre-diabetes, Type-2 diabetes, and hyperlipidemia, to name a few. Currently, Wegovy™ is generally not covered by insurance and costs about $1,300 per month. We now offer it to our patients at $600 per month.
Semaglutide is safe and well-tolerated, with minimal side effects. When people do get side effects, they are generally mild and often improve over time. To minimize their occurrence the semaglutide is started at a very low dose and increased gradually over 5 weeks. Studies show that maximal weight loss is achieved at the maximal dose. The most common side effects of semaglutide are gastro-intestinal such as nausea, vomiting, abdominal pain, heartburn, bloating, diarrhea, constipation, upset stomach, belching, and gas. Fatigue, headache, tiredness, and dizziness are less common.
Additional Benefits Besides Weight Loss
- Improves Blood Pressure
- Reduces Hemoglobin A1C and Improves Fasting Blood Sugar
- Lowers Cholesterol and Triglycerides
- Reduces Belly Fat and Waist Measurement
- Reduces Inflammation
- Improves Physical Functioning
- Increases Lean Body Mass Percentage